I use Quadro M1200 laptop with Xenon processor (year old) laptop. It works very well. Your machine is very powerful. Here are few things that can help,

1. Make sure your computer is actually using the dedicated video card (more performance) and not the video card in-built to the mother board (saves power). By default the computer (maybe it is a laptop only thing) is setup to decide which card to use. You can see that in the Nvdia Control panel by right clicking on your desktop and specify your preference there.

2. If you have not already tried it, update the video card drivers and then try again.

3. Are you using the same config settings for these comparisons.

4. Also try opengl2 drivers (you have already tried driectx 11, directx 9).