If it's a matter of avoiding manual input of node numbers on the ISOs, you can set up CAESAR line numbers to match ISO numbers instead, and have CAESAR push out ISOs with node numbers that roughly correlate to the ISOs from CADWorx.

I understand that this doesn't cut out the ISO / Node number from your workflow, but it could alleviate Node Number write-ups and their subsequent errors. It could also mean that you can fork over "your" ISOs and "their" ISOs to someone else to mark up, instead of a CAESAR operator.

I can't really help on the CADWorx/CAESAR functionality, unfortunately.