The forces and moments have nothing to do with the orientation of your nozzle. The attached piping system imparts forces and moments at the nozzle anchor due to gravity, wind, thermal expansion, etc. They can act in any direction, depending on the routing of your piping system. The XYZ axis system just gives us a frame work to represent the total force and moment by means of component vectors.
_________________________
Edward L. Klein
Pipe Stress Engineer
All the world is a Spring