my opinion:
You should check nozzle load in
1)Hydrotest case, if your piping system need hydrotest
2)SUS case,
3)OPE case, design temperature
4)OPE + wind, if your piping system is not shielded by building.
5)OPE +seismic, if your piping is located in an area which need to be consider seismic load.
6)steam/ liquid hammer case.
etc....