1) The values from Appendix F are substituted directly into the equations in Table 5-21. The multipliers you reference are applied in F.7.5 as an increase factor to the failure pressure. The failure pressure is not increased by 1.5, so therefore the 1.5 in Table 5-21 is also applicable.
2) Again for F.7.5, the 1.25 multiplier is applied with the failure pressure. Where do you see a 1.25 multiplier in Table 5-21?
3) I believe these factors in F.7.5 would apply regardless of the status of Appendix M.
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Regards,
Richard Ay - Consultant