Dear Beginner,
I would encourage you to visit the website of Paulin Research Group for some informative articles on SIF,Fatigue , Markl's curve, factor of safety used on cycles and stress and also read the document NUREG CR3243.You will get the answer that you are looking for.The important thing is to understand what Markl did ,how he did and how the curves were generated.NUREG CR3243 will explain you the diference between approaches of B31 and the SEC VIII and SEC III approaches.
Regards
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anindya